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KMID : 0352819850010010063
Kosin Medical Journal
1985 Volume.1 No. 1 p.63 ~ p.72
Primary Mixed Malignancies of Lung


Abstract
Primary mixed malignancy of the lung- carcinosarcoma and pulmonary blastoma-are rare malignant neoplasms that contain both carcinomatous and sarcomatous components intermingled. Since the original description of pulmonary carcino! arcoma, about 44 cases have been reported in the literature¢¥ " In 1945, a second. type of mixed pulmonary malignancy was
reported by Barrett and Barnard in which the carcinoma and sarcoma morphologically resembled embryonic lung in that well-differentiated, epithelial-lined tubules were distributed in a sarcomatous background that resembled primitive mesenchyme. They later named this tumor embryoma. In 1961, Spencer "¢¥ reported three new cases and suggested the name pulmonary blastoma because of the resemblance to Wilms¢¥ tumor and his concpt that these tumors arose from primitive pleuri-potential mesenchyme (blastema). About 50 cases similar to that of pulmonary blastoma have been reported in the literature and one case have reported in the domestic area ¢¥*¢¥
The purpose of this paper is to review the literature and to present our new cases, one pulmonary blastoma and one carcinosarcoma, which occured in male parients of 39 and 45 years of age, respectively, and to compare the clinicopathologic
features of carcinosarcoma of the lung and pulmonary blastoma.
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